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Our main findings were that (i) DRESS, regardless of HIV status, was associated with an increased skin infiltration of CD8+ T-cells compared to normal skin, (ii) CD4+ T-cells were lower in the skin of HIV-positive DRESS cases compared to HIV-negative cases, (iii) the dermal infiltration of CD4+FoxP3+ T-cells was higher in HIV-positive DRESS cases reacting to more than one drug

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