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For select patients, including those with substantial comorbidities that are known to impair wound healing and/or response to infection (e.g., complex hosts), or those who have a clinically complex wound, NPWT with application of cleansing solution may be used.[1] See indications for each type of NPWT device in the section 'General Indications and Contraindications' in topic "Negative Pressure Wound Therapy"

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